Poultry are sensitive to biotic transitions throughout their lives, and even more so during critical phases such as the start or end of a batch. Suboptimal conditions (poor chick quality, short sanitary break, feed transition and quality, high bacterial pressure, and viral transmission) can weaken cellular homeostasis and lead to decreased performance or even mortality.
In this context, biotic stress causes a decline in zootechnical performance. At the cellular level, bacterial or viral infection induces a disruption in homeostasis, which can cause oxidative stress that impacts metabolism. At the organism level, this also leads to a redistribution of energy and metabolic resources to enable the immune system to defend itself, to the detriment of performance.
That is why Biodevas Laboratoires recently Biodevas Laboratoires ICEN, to better manage biotic stress and maintain performance during critical phases of poultry farming.
Its mode of action is based on four actions:
- Managing oxidative stress in an innovative and unique way by stimulating the synthesis of antioxidant enzymes in order to maintain cellular homeostasis and thus its functioning.
- Strengthening the integrity of epithelia by acting on tight junctions to limit the impact of damage on mucous membranes and enable them to fully perform their role as a barrier against bacteria and viruses.
- Regulation of inflammation through modulation of pro- and anti-inflammatory cytokines,
- Stimulation of the immune system by facilitating the recruitment of cells involved in an adequate response, enabling the animal to be more resistant to pathogens.
In multiple trials conducted under real operating conditions, ICEN mortality and culling related to E. coli and reduced the incidence ofEnterococcus cecorum. In a recent trial in Germany involving 100,000 broiler chickens, ICEN possible to avoid the use of antibiotics (lincomycin + spectinomycin) at the start of the rearing period for poor-quality chicks, while maintaining zootechnical performance similar to that of batches receiving antimicrobials. ICEN therefore in line with the restriction of antibiotic treatments in Germany and is proving to be a natural, non-biocidal alternative to antibiotics, particularly for managing the impact of colibacillosis, lameness linked to Enterococcus cecorum and, more generally, viral outbreaks and periods of biotic stress.
